HAMP Antibody

CAT: 0247-OACD00328-1MLSize: 1 mLDry Ice: NoHazardous: No
CAT#:0247-OACD00328-1MLSize:1 mL
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CAS Number
9007-83-4
Gene Name
Hepcidin antimicrobial peptide
Gene Aliases
HEPC; hepcidin; hepcidin preproprotein; HFE2B; LEAP1; liver-expressed antimicrobial peptide 1; PLTR; putative liver tumor regressor.
Gene ID
57817
Accession Number
NP_066998.1
Reactivity
Human
Immunogen
Recombinant Hepc (Ser25~Thr84) expressed in E.coli
Target
Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes (PubMed:22306005) .
Clonality
Monoclonal
Clone
D7
Type
Monoclonal Antibody
Applications
Immunohistochemistry|Western blot
Purification
Protein A/G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Fragment
IgG2b, kappa
NCBI Gene Symbol
HAMP
Host or Source
Mouse
Protein Name
Hepcidin
Gene Name URL
HAMP
Nucleotide Accession Number
NM_021175.3

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