Products for Research Use Only
RegisterLogin

VAV3 Antibody

CAT: 0247-OACA10720-100UGSize: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OACA10720-100UGSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
Vav guanine nucleotide exchange factor 3
Gene Aliases
Guanine nucleotide exchange factor VAV3; vav 3 guanine nucleotide exchange factor; vav 3 oncogene; VAV-3.
Gene ID
10451
Accession Number
NP_001073343
Reactivity
Human|Mouse|Rat
Immunogen
Recombinant Human Guanine nucleotide exchange factor VAV3 protein (562-674AA)
Target
Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity) . May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organization and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2 (ITGB2) -mediated macrophage adhesion and, to a lesser extent, contributes to beta-3 (ITGB3) -mediated adhesion. Does not affect integrin beta-1 (ITGB1) -mediated adhesion (By similarity) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
VAV3
Host or Source
Rabbit
Protein Name
Guanine nucleotide exchange factor VAV3
Gene Name URL
VAV3
Nucleotide Accession Number
NM_001079874

Related Products

CatalogName
OPCD07864-50UGVAV3 Recombinant Protein
OPCD07865-50UGVAV3 Recombinant Protein
OPCD07864-200UGVAV3 Recombinant Protein
OPCD07865-10UGVAV3 Recombinant Protein
OCOA12274-20UGVAV3 Protein Lysate
OCOA15512-20UGVAV3 Protein Lysate
OPCD07865-200UGVAV3 Recombinant Protein
OPCD07864-10UGVAV3 Recombinant Protein
OKEH00310-96WVAV3 ELISA Kit (Human)
OKEH03064-96WVAV3 ELISA Kit (Mouse)

Alternative Products

CatalogName
70R-34663VAV3 antibody

Popular Products