RB1CC1 Antibody

9007-83-4

RB1 inducible coiled-coil 1

200 kDa FAK family kinase-interacting protein; ATG17; CC1; FAK family kinase-interacting protein of 200 kDa; FIP200; phosphatase 1, regulatory subunit 131; PPP1R131; RB1-inducible coiled-coil protein 1.

9821

NP_001077086

Human

Recombinant Human RB1-inducible coiled-coil protein 1 protein (1544-1594AA)

Involved in autophagy (PubMed:21775823) . Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1 (PubMed:23392225) . Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) during S.typhimurium infection and subsequent xenophagy (By similarity) . Involved in repair of DNA damage caused by ionizing radiation, which subsequently improves cell survival by decreasing apoptosis (By similarity) . Inhibits PTK2/FAK1 and PTK2B/PYK2 kinase activity, affecting their downstream signaling pathways (PubMed:10769033, PubMed:12221124) . Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111 (By similarity) . Functions as a DNA-binding transcription factor (PubMed:12095676) . Is a potent regulator of the RB1 pathway through induction of RB1 expression (PubMed:14533007) . Plays a crucial role in muscular differentiation (PubMed:12163359) . Plays an indispensable role in fetal hematopoiesis and in the regulation of neuronal homeostasis (By similarity) .

Unconjugated

Polyclonal Antibody

Enzyme-linked immunosorbent assay|Immunofluorescence

Protein G Purified

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Liquid

-20°C or -80°C

IgG

RB1CC1

Rabbit

RB1-inducible coiled-coil protein 1

RB1CC1