Products for Research Use Only
RegisterLogin

SNX27 Antibody

CAT: 0247-OACA10633-100UGSize: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OACA10633-100UGSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
Sorting nexin 27
Gene Aliases
Methamphetamine-responsive transcript 1; MRT1; MY014; sorting nexin family member 27; sorting nexin-27.
Gene ID
81609
Accession Number
NP_001317652
Reactivity
Human
Immunogen
Recombinant Human Sorting nexin-27 protein (458-497AA)
Target
Involved in the retrograde transport from endosome to plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins. Following internalization, endocytosed transmembrane proteins are delivered to early endosomes and recycled to the plasma membrane instead of being degraded in lysosomes. SNX27 specifically binds and directs sorting of a subset of transmembrane proteins containing a PDZ-binding motif at the C-terminus: following interaction with target transmembrane proteins, associates with the retromer complex, preventing entry into the lysosomal pathway, and promotes retromer-tubule based plasma membrane recycling. SNX27 also binds with the WASH complex. Interacts with membranes containing phosphatidylinositol-3-phosphate (PtdIns (3P) ) . May participate in establishment of natural killer cell polarity. Recruits CYTIP to early endosomes.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
SNX27
Host or Source
Rabbit
Protein Name
Sorting nexin-27
Gene Name URL
SNX27
Nucleotide Accession Number
NM_001330723

Related Products

CatalogName
OCOA02808-20UGSNX27 Protein Lysate
AAP91023-100UGSNX27 Peptide - middle region (AAP91023)
AAP81595-100UGSNX27 Peptide - N-terminal region (AAP81595)
AAP84846-100UGSNX27 Peptide - N-terminal region (AAP84846)
AAP65386-100UGSNX27 Peptide - C-terminal region (AAP65386)
OACD07405-100ULSNX17 Antibody
OACA10066-50UGSNX17 Antibody
OACA03703-50UGSNX24 Antibody
OACA04075-50UGSNX22 Antibody
OAAL00904-100UGSNX20 Antibody

Alternative Products

CatalogName
70R-20442SNX27 antibody

Popular Products