SAMD8 Antibody

• Gene Name:

  Sterile alpha motif domain containing 8

• Gene Aliases:

  Ceramide phosphoethanolamine synthase; CPE synthase; epididymis luminal protein 177; epididymis secretory sperm binding protein Li 181mP; HEL-177; HEL-S-181mP; SAM domain-containing protein 8; SMSr; sphingomyelin synthase related; sphingomyelin synthase-related protein 1; sterile alpha motif domain-containing protein 8.

• Gene ID:

  142891

• Accession Number:

  NP_001167627

• Reactivity:

  Human

• Immunogen:

  Recombinant Human Sphingomyelin synthase-related protein 1 protein (1-152AA)

• Target:

  Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunohistochemistry

• Purification:

  Protein G Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format:

  Liquid

• Reconstitution:

  -20°C or -80°C

• Fragment:

  IgG

• NCBI Gene Symbol:

  SAMD8

• Host or Source:

  Rabbit

• Protein Name:

  Sphingomyelin synthase-related protein 1

• Gene Name URL:

  SAMD8

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001174156