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DNAJB6 Antibody

CAT: 0247-OACA10046-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OACA10046-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
DnaJ heat shock protein family (Hsp40) member B6
Gene Aliases
DJ4; DnaJ; DnaJ (Hsp40) homolog, subfamily B, member 6; dnaJ homolog subfamily B member 6; DnaJ-like 2 protein; heat shock protein J2; HHDJ1; HSJ2; HSJ-2; LGMD1D; LGMD1E; LGMDD1; MRJ; MSJ-1.
Gene ID
10049
Accession Number
NP_005485
Reactivity
Human|Mouse
Immunogen
Recombinant Human DnaJ homolog subfamily B member 6 protein (208-326AA)
Target
Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Isoform B but not isoform A inhibits huntingtin aggregation. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Western blot
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
DNAJB6
Host or Source
Rabbit
Protein Name
DnaJ homolog subfamily B member 6
Gene Name URL
DNAJB6
Nucleotide Accession Number
NM_005494

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