PFKL Antibody

• Gene Name :

  Phosphofructokinase, liver type

• Gene Aliases :

  6-phosphofructokinase type B;6-phosphofructokinase, liver type; ATP-dependent 6-phosphofructokinase, liver type; ATP-PFK; liver-type 1-phosphofructokinase; PFK-B; PFK-L; phosphofructo-1-kinase isozyme B; phosphohexokinase.

• Gene ID :

  5211

• Accession Number :

  NP_001002021

• Reactivity :

  Human|Mouse

• Immunogen :

  Recombinant Human ATP-dependent 6-phosphofructokinase, liver type protein (229-479AA)

• Target :

  Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (PubMed:22923583) . Negatively regulates the phagocyte oxidative burst in response to bacterial infection by controlling cellular NADPH biosynthesis and NADPH oxidase-derived reactive oxygen species. Upon macrophage activation, drives the metabolic switch toward glycolysis, thus preventing glucose turnover that produces NADPH via pentose phosphate pathway (By similarity) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Western blot

• Purification :

  Protein G Purified

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format :

  Liquid

• Reconstitution :

  -20°C or -80°C

• Fragment :

  IgG

• NCBI Gene Symbol :

  PFKL

• Host or Source :

  Rabbit

• Protein Name :

  ATP-dependent 6-phosphofructokinase, liver type

• Gene Name URL :

  PFKL

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_001002021