BCL11B Antibody

• Gene Name:

  BAF chromatin remodeling complex subunit BCL11B

• Gene Aliases:

  ATL1; ATL1-alpha; ATL1-beta; ATL1-delta; ATL1-gamma; B cell CLL/lymphoma 11B; B-cell CLL/lymphoma 11B; B-cell CLL/lymphoma 11B (zinc finger protein) ; B-cell CLL/lymphoma 11B/T-cell receptor delta constant region fusion protein; B-cell lymphoma/leukaemia 11B; B-cell lymphoma/leukemia 11B; BCL-11B; BCL11B, BAF complex component; BCL11B/TRDC fusion; COUP-TF-interacting protein 2; CTIP2; CTIP-2; hRit1; hRIT1-alpha; IDDFSTA; IMD49; radiation-induced tumor suppressor gene 1 protein; RIT1; SMARCM2; zinc finger protein hRit1 alpha; ZNF856B.

• Gene ID:

  64919

• Accession Number:

  NP_001269166

• Reactivity:

  Human

• Immunogen:

  Recombinant Human B-cell lymphoma/leukemia 11B protein (500-550AA)

• Target:

  Key regulator of both differentiation and survival of T-lymphocytes during thymocyte development in mammals. Essential in controlling the responsiveness of hematopoietic stem cells to chemotactic signals by modulating the expression of the receptors CCR7 and CCR9, which direct the movement of progenitor cells from the bone marrow to the thymus (PubMed:27959755) . Is a regulator of IL2 promoter and enhances IL2 expression in activated CD4 (+) T-lymphocytes (PubMed:16809611) . Tumor-suppressor that represses transcription through direct, TFCOUP2-independent binding to a GC-rich response element (By similarity) . May also function in the P53-signaling pathway (By similarity) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunohistochemistry

• Purification:

  Protein G Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format:

  Liquid

• Reconstitution:

  -20°C or -80°C

• Fragment:

  IgG

• NCBI Gene Symbol:

  BCL11B

• Host or Source:

  Rabbit

• Protein Name:

  B-cell lymphoma/leukemia 11B

• Gene Name URL:

  BCL11B

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001282237