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ABCG8 Antibody

CAT: 0247-OACA09693-50UGSize: 50 µgDry Ice: NoHazardous: No
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CAT#:0247-OACA09693-50UGSize:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
ATP binding cassette subfamily G member 8
Gene Aliases
ATP-binding cassette sub-family G member 8; ATP-binding cassette, sub-family G (WHITE), member 8; GBD4; sterolin 2; Sterolin-2; STSL; STSL1.
Gene ID
64241
Accession Number
NP_071882
Reactivity
Human|Mouse
Immunogen
Recombinant Human ATP-binding cassette sub-family G member 8 protein (176-413AA)
Target
ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg (2+) - and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed:11099417, PubMed:11452359, PubMed:27144356, PubMed:15054092) . Required for normal sterol homeostasis (PubMed:11099417, PubMed:11452359, PubMed:15054092) . The heterodimer with ABCG5 has ATPase activity (PubMed:16893193, PubMed:20210363, PubMed:27144356) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Western blot
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
ABCG8
Host or Source
Rabbit
Protein Name
ATP-binding cassette sub-family G member 8
Gene Name URL
ABCG8
Nucleotide Accession Number
NM_022437