Products for Research Use Only
RegisterLogin

WAC Antibody

CAT: 0247-OACA09674-100UGSize: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OACA09674-100UGSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
WW domain containing adaptor with coiled-coil
Gene Aliases
BM-016; DESSH; PRO1741; WW domain-containing adapter protein with coiled-coil; Wwp4.
Gene ID
51322
Accession Number
NP_057712
Reactivity
Human
Immunogen
Recombinant Human WW domain-containing adapter protein with coiled-coil protein (10-102AA)
Target
Acts as a linker between gene transcription and histone H2B monoubiquitination at 'Lys-120' (H2BK120ub1) (PubMed:21329877) . Interacts with the RNA polymerase II transcriptional machinery via its WW domain and with RNF20-RNF40 via its coiled coil region, thereby linking and regulating H2BK120ub1 and gene transcription (PubMed:21329877) . Regulates the cell-cycle checkpoint activation in response to DNA damage (PubMed:21329877) . Positive regulator of amino acid starvation-induced autophagy (PubMed:22354037) . Also acts as a negative regulator of basal autophagy (PubMed:26812014) . Positively regulates MTOR activity by promoting, in an energy-dependent manner, the assembly of the TTT complex composed of TELO2, TTI1 and TTI2 and the RUVBL complex composed of RUVBL1 and RUVBL2 into the TTT-RUVBL complex. This leads to the dimerization of the mTORC1 complex and its subsequent activation (PubMed:26812014) . May negatively regulate the ubiquitin proteasome pathway (PubMed:21329877) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
WAC
Host or Source
Rabbit
Protein Name
WW domain-containing adapter protein with coiled-coil
Gene Name URL
WAC
Nucleotide Accession Number
NM_016628

Related Products

CatalogName
OCOA10143-20UGWAC Protein Lysate
OPCA04339-20UGWAC Recombinant Protein (Bacteriophage T4)
AAP87488-100UGWAC Peptide - middle region (AAP87488)
OPCA04339-100UGWAC Recombinant Protein (Bacteriophage T4)
OPCA04339-1MGWAC Recombinant Protein (Bacteriophage T4)
AAP59223-100UGWAC Peptide - N-terminal region (AAP59223)
OACD01074-100ULWAS Antibody
OAMA00822-1MGWAS Antibody
OAMA00821-1MGWAS Antibody
OASG07565-100ULWAS Antibody

Alternative Products

CatalogName
MBS8529199-01H2B Antibody Antibody
MBS8513599-01CD11b Antibody Antibody
DF8746-01ASAP1 antibody Antibody
MBS850197-01Antibody to IGFBP2 Antibody
E36403ZNF98 Antibody Antibody
GWB-250026Lck antibody Antibody
E8M1007-4HSP60 Antibody Antibody
MBS9403836-01SZT2 Antibody Antibody
LSMab09882anti-Antibody^Polyclonal antibody control antibody
GWB-5C6547MAD1L1 antibody [9B10] Antibody

Popular Products