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KDM5C Antibody

CAT: 0247-OACA09408-50UGSize: 50 µgDry Ice: NoHazardous: No
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CAT#:0247-OACA09408-50UGSize:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Lysine demethylase 5C
Gene Aliases
[histone H3]-trimethyl-L-lysine (4) demethylase 5C; DXS1272E; histone demethylase JARID1C; JARID1C; JmjC domain-containing protein SMCX; Jumonji, AT rich interactive domain 1C (RBP2-like) ; Jumonji/ARID domain-containing protein 1C; lysine (K) -specific demethylase 5C; lysine-specific demethylase 5C; MRX13; MRXJ; MRXSCJ; MRXSJ; Protein SmcX; Protein Xe169; SMCX; Smcx homolog, X chromosome; Smcy homolog, X-linked; XE169.
Gene ID
8242
Accession Number
NP_001140174
Reactivity
Human
Immunogen
Recombinant Human Lysine-specific demethylase 5C protein (45-324AA)
Target
Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code (PubMed:28262558) . Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
KDM5C
Host or Source
Rabbit
Protein Name
Lysine-specific demethylase 5C
Gene Name URL
KDM5C
Nucleotide Accession Number
NM_001146702

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