Products for Research Use Only
RegisterLogin

ATP8B1 Antibody

CAT: 0247-OACA09340-100UGSize: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OACA09340-100UGSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
ATPase phospholipid transporting 8B1
Gene Aliases
ATPase class I type 8B member 1; ATPase, aminophospholipid transporter, class I, type 8B, member 1; ATPase, class I, type 8B, member 1; ATPIC; BRIC; E1-E2 ATPase; familial intrahepatic cholestasis type 1; FIC1; ICP1; P4-ATPase flippase complex alpha subunit ATP8B1; PFIC; PFIC1; phospholipid-transporting ATPase IC; probable phospholipid-transporting ATPase IC.
Gene ID
5205
Accession Number
NP_005594
Reactivity
Human
Immunogen
Recombinant Human Phospholipid-transporting ATPase IC protein (217-330AA)
Target
Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. May play a role in asymmetric distribution of phospholipids in the canicular membrane. May have a role in transport of bile acids into the canaliculus, uptake of bile acids from intestinal contents into intestinal mucosa or both. In cooperation with ABCB4 may be involved in establishing integrity of the canalicular membrane thus protecting hepatocytes from bile salts. Together with TMEM30A is involved in uptake of the synthetic drug alkylphospholipid perifosine. Involved in the microvillus formation in polarized epithelial cells; the function seems to be independent from its flippase activity. Required for the preservation of cochlear hair cells in the inner ear. May act as cardiolipin transporter during inflammatory injury.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
ATP8B1
Host or Source
Rabbit
Protein Name
Phospholipid-transporting ATPase IC
Gene Name URL
ATP8B1
Nucleotide Accession Number
NM_005603

Related Products

CatalogName
OACA09730-50UGATP8A1 Antibody
OAEB00948-100UGATP1B1 Antibody
OACA09730-100UGATP8A1 Antibody
OAGA07845-100ULATP2B1 Antibody
OAAJ07939-100ULATP1B1 Antibody
OACA10103-50UGATP8A2 Antibody
OACD01848-100ULATP1B3 Antibody
OAAN03740-200ULATP1A1 Antibody
OACD01849-100ULATP1B3 Antibody
OACD01850-100ULATP1B3 Antibody

Alternative Products

CatalogName
MBS7046351-01ATP8B1 Antibody
CAC10929-01Atp8B1 Polyclonal Antibody
GTR17905128-01ATP8B1 Antibody (Biotin)
GTR17905126-01ATP8B1 Antibody (HRP)
GTR17905127-01ATP8B1 Antibody (FITC)
A13633-100UGATP8B1 Antibody, FITC conjugated
MBS7043712-01ATP8B1 Antibody, Biotin conjugated
MBS7046104-01ATP8B1 Antibody, HRP conjugated
abx312597-01Phospholipid-Transporting ATPase IC (ATP8B1) Antibody
abx312598-01Phospholipid-Transporting ATPase IC (ATP8B1) Antibody (HRP)

Popular Products