MRC2 Antibody

CAT: 0247-OACA09075-100ULSize: 100 µLDry Ice: NoHazardous: No
CAT#:0247-OACA09075-100ULSize:100 µL
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CAS Number
9007-83-4
Gene Name
Mannose receptor C type 2
Gene Aliases
CD280; CLEC13E; C-type lectin domain family 13 member E; C-type mannose receptor 2; ENDO180; endocytic receptor (macrophage mannose receptor family) ; endocytic receptor 180; macrophage mannose receptor 2; UPARAP; UPAR-associated protein; urokinase-type plasminogen activator receptor-associated protein.
Gene ID
9902
Accession Number
NP_006030
Reactivity
Human
Immunogen
Recombinant Human C-type mannose receptor 2 protein (120-300AA)
Target
May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
MRC2
Host or Source
Rabbit
Protein Name
C-type mannose receptor 2
Gene Name URL
MRC2
Nucleotide Accession Number
NM_006039

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