Products for Research Use Only
RegisterLogin

MYLIP Antibody

CAT: 0247-OACA08782-50ULSize: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OACA08782-50ULSize:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
Myosin regulatory light chain interacting protein
Gene Aliases
Band 4.1 superfamily member BZF1; cellular modulator of immune recognition (c-MIR) ; E3 ubiquitin ligase-inducible degrader of the low density lipoprotein receptor; E3 ubiquitin-protein ligase MYLIP; IDOL; inducible degrader of the LDL-receptor; MIR; Myosin regulatory light chain interacting protein; RING-type E3 ubiquitin transferase MYLIP.
Gene ID
29116
Accession Number
NP_037394
Reactivity
Human|Mouse
Immunogen
Recombinant Human E3 ubiquitin-protein ligase MYLIP protein (266-445AA)
Target
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
MYLIP
Host or Source
Rabbit
Protein Name
E3 ubiquitin-protein ligase MYLIP
Gene Name URL
MYLIP
Nucleotide Accession Number
NM_013262

Related Products

CatalogName
OPCA03059-20UGMYLIP Recombinant Protein
OPCA03059-100UGMYLIP Recombinant Protein
OCOA11436-20UGMYLIP Protein Lysate
OKCA01214-96WMYLIP ELISA Kit (Human)
OKCA01214MYLIP ELISA Kit (Human) (OKCA01214)
AAP43136-100UGMYLIP Peptide - middle region (AAP43136)
OPCA03059-500UGOPCA03059-500UG - MYLIP Recombinant Protein
OPCA00297-1MGRecombinant human E3 ubiquitin- protein ligase MYLIP
OPCA00297-20UGRecombinant human E3 ubiquitin- protein ligase MYLIP
OPCA00297-100UGRecombinant human E3 ubiquitin- protein ligase MYLIP

Alternative Products

CatalogName
70R-35400MYLIP antibody

Popular Products