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LFNG Antibody

CAT: 0247-OACA08458-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OACA08458-100ULSize:100 µL
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CAS Number
9007-83-4
Gene Name
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Gene Aliases
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; SCDO3.
Gene ID
3955
Accession Number
NP_001035257
Reactivity
Human|Mouse
Immunogen
Recombinant Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe protein (1-250AA)
Target
Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1 (By similarity) . Decreases the binding of JAG1 to NOTCH2 but not that of DLL1 (PubMed:11346656) . Essential mediator of somite segmentation and patterning (By similarity) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
LFNG
Host or Source
Rabbit
Protein Name
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
Gene Name URL
LFNG
Nucleotide Accession Number
NM_001040167

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