COPS3 Antibody

CAT: 0247-OACA08148-50ULSize: 50 µLDry Ice: NoHazardous: No
CAT#:0247-OACA08148-50ULSize:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
9007-83-4
Gene Name
COP9 signalosome subunit 3
Gene Aliases
COP9 complex subunit 3; COP9 constitutive photomorphogenic homolog subunit 3; COP9 signalosome complex subunit 3; CSN3; JAB1-containing signalosome subunit 3; SGN3; signalosome subunit 3.
Gene ID
8533
Accession Number
NP_001186054
Reactivity
Human|Mouse
Immunogen
Recombinant Human COP9 signalosome complex subunit 3 protein (194-423AA)
Target
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
COPS3
Host or Source
Rabbit
Protein Name
COP9 signalosome complex subunit 3
Gene Name URL
COPS3
Nucleotide Accession Number
NM_001199125

Related Products

CatalogName
OCOA21383-20UGCOPS3 Protein Lysate
OCOA13500-20UGCOPS3 Protein Lysate
OACA12576-100ULCOPS3 Recombinant Antibody [3F9] (OACA12576)
AAP59347-100UGCOPS3 Peptide - C-terminal region (AAP59347)
AAP59348-100UGCops3 Peptide - C-terminal region (AAP59348)
OACA07672-100ULCOPS4 Antibody
OACA06925-50ULCOPS2 Antibody
OAGA05774-100ULCOPS4 Antibody
OAGA05426-100ULCOPS2 Antibody
OAGA05875-100ULCOPS4 Antibody

Alternative Products

CatalogName
MBS8510682-01COPS3 Antibody

Popular Products