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QKI Antibody

CAT: 0247-OACA08094-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OACA08094-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
QKI, KH domain containing RNA binding
Gene Aliases
Homolog of mouse quaking QKI (KH domain RNA binding protein) ; Hqk; hqkI; protein quaking; QK; QK1; QK3; QKI/LOC100132735 fusion; quaking homolog, KH domain RNA binding; RNA binding protein HQK.
Gene ID
9444
Accession Number
NP_001288014
Reactivity
Human
Immunogen
Recombinant Human Protein quaking protein (1-341AA)
Target
RNA-binding protein that plays a central role in myelinization (PubMed:16641098) . Binds to the 5'-NACUAAY-N (1,20) -UAAY-3' RNA core sequence. Regulates target mRNA stability (PubMed:23630077) . In addition, acts by regulating pre-mRNA splicing, mRNA export and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia (PubMed:16641098) . Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
QKI
Host or Source
Rabbit
Protein Name
Protein quaking
Gene Name URL
QKI
Nucleotide Accession Number
NM_001301085

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