Products for Research Use Only
RegisterLogin

ROCK2 Antibody

CAT: 0247-OACA07795-50ULSize: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OACA07795-50ULSize:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
Rho associated coiled-coil containing protein kinase 2
Gene Aliases
P164 ROCK-2; Rho kinase 2; rho-associated protein kinase 2; Rho-associated, coiled-coil-containing protein kinase 2; rho-associated, coiled-coil-containing protein kinase II; ROCK-II.
Gene ID
9475
Accession Number
NP_001308572
Reactivity
Human|Rat
Immunogen
Recombinant Human Rho-associated protein kinase 2 protein (1109-1388AA)
Target
Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p90RSK/RPS6KA1 during myogenic differentiation. Plays an important role in the timely initiation of centrosome duplication. Inhibits keratinocyte terminal differentiation. May regulate closure of the eyelids and ventral body wall through organization of actomyosin bundles. Plays a critical role in the regulation of spine and synaptic properties in the hippocampus. Plays an important role in generating the circadian rhythm of the aortic myofilament Ca (2+) sensitivity and vascular contractility by modulating the myosin light chain phosphorylation.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
ROCK2
Host or Source
Rabbit
Protein Name
Rho-associated protein kinase 2
Gene Name URL
ROCK2
Nucleotide Accession Number
NM_001321643

Related Products

CatalogName
AAP61467-100UGROCK2
OPCD06735-50UGROCK2 Recombinant Protein
OPCD06735-200UGROCK2 Recombinant Protein
OPCD06735-10UGROCK2 Recombinant Protein
OCOA12877-20UGROCK2 Protein Lysate
OACA12294-100ULROCK2 Recombinant Antibody [10E1] (OACA12294)
OABB00251-100UGOABB00251-100UG - ROCK2 Polyclonal Antibody
OKEH06433-96WROCK2 ELISA Kit (Rat)
OKCD07732-96WROCK2 ELISA Kit (Human)
OKEH04726-96WROCK2 ELISA Kit (Human)

Alternative Products

CatalogName
70R-50715ROCK2 antibody

Popular Products