MEF2C Antibody

CAT: 0247-OACA07588-100ULSize: 100 µLDry Ice: NoHazardous: No
CAT#:0247-OACA07588-100ULSize:100 µL
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CAS Number
9007-83-4
Gene Name
Myocyte enhancer factor 2C
Gene Aliases
C5DELq14.3; DEL5q14.3; MADS box transcription enhancer factor 2, polypeptide C; Myocyte enhancer factor 2C; myocyte-specific enhancer factor 2C; NEDHSIL.
Gene ID
4208
Accession Number
NP_001124477
Reactivity
Human
Immunogen
Recombinant Human Myocyte-specific enhancer factor 2C protein (170-380AA)
Target
Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture (By similarity) . Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
MEF2C
Host or Source
Rabbit
Protein Name
Myocyte-specific enhancer factor 2C
Gene Name URL
MEF2C
Nucleotide Accession Number
NM_001131005

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