Products for Research Use Only
RegisterLogin

APBB1 Antibody

CAT: 0247-OACA07361-100ULSize: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OACA07361-100ULSize:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
Amyloid beta precursor protein binding family B member 1
Gene Aliases
Adaptor protein FE65a2; amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) ; amyloid-beta A4 precursor protein-binding family B member 1; FE65; MGC:9072; Protein Fe65; RIR; stat-like protein.
Gene ID
322
Accession Number
NP_001155
Reactivity
Human
Immunogen
Recombinant Human Amyloid beta A4 precursor protein-binding family B member 1 protein (361-710AA)
Target
Transcription coregulator that can have both coactivator and corepressor functions. Adapter protein that forms a transcriptionally active complex with the gamma-secretase-derived amyloid precursor protein (APP) intracellular domain. Plays a central role in the response to DNA damage by translocating to the nucleus and inducing apoptosis. May act by specifically recognizing and binding histone H2AX phosphorylated on 'Tyr-142' (H2AXY142ph) at double-strand breaks (DSBs), recruiting other pro-apoptosis factors such as MAPK8/JNK1. Required for histone H4 acetylation at double-strand breaks (DSBs) . Its ability to specifically bind modified histones and chromatin modifying enzymes such as KAT5/TIP60, probably explains its transcription activation activity. Function in association with TSHZ3, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. Associates with chromatin in a region surrounding the CASP4 transcriptional start site (s) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
APBB1
Host or Source
Rabbit
Protein Name
Amyloid-beta A4 precursor protein-binding family B member 1
Gene Name URL
APBB1
Nucleotide Accession Number
NM_001164

Related Products

CatalogName
OCOA05997-20UGAPBB1 Protein Lysate
OCOA00413-20UGAPBB1 Protein Lysate
OAEB01135-100UGGoat Anti-APBB1 / FE65 Antibody
AAP55471-100UGApbb1 Peptide - N-terminal region (AAP55471)
AAP75919-100UGAPBB1 Peptide - N-terminal region (AAP75919)
OAGA03544-100ULAPBB2 Antibody
OAAF03273-100UGAPBB2 Antibody
OACD01698-1MLAPBB3 Antibody
OAAJ04652-100ULAPBB2 Antibody
OAGA03453-100ULAPBB3 Antibody

Alternative Products

CatalogName
70R-9328Apbb1 antibody

Popular Products