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SH3GLB1 Antibody

CAT: 0247-OACA07244-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OACA07244-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
SH3 domain containing GRB2 like, endophilin B1
Gene Aliases
Bax-interacting factor 1; Bif-1; CGI-61; dJ612B15.2; endophilin-B1; PPP1R70; protein phosphatase 1, regulatory subunit 70; SH3 domain-containing GRB2-like protein B1; SH3-containing protein SH3GLB1; SH3-domain GRB2 like endophilin B1; testicular tissue protein Li 172.
Gene ID
51100
Accession Number
NP_001193580
Reactivity
Human|Mouse
Immunogen
Recombinant Human Endophilin-B1 protein (1-365AA)
Target
May be required for normal outer mitochondrial membrane dynamics (PubMed:15452144) . Required for coatomer-mediated retrograde transport in certain cells (By similarity) . May recruit other proteins to membranes with high curvature. May promote membrane fusion (PubMed:11604418) . Involved in activation of caspase-dependent apoptosis by promoting BAX/BAK1 activation (PubMed:16227588) . Isoform 1 acts proapoptotic in fibroblasts (By similarity) . Involved in caspase-independent apoptosis during nutrition starvation and involved in the regulation of autophagy. Activates lipid kinase activity of PIK3C3 during autophagy probably by associating with the PI3K complex II (PI3KC3-C2) (PubMed:17891140) . Associated with PI3KC3-C2 during autophagy may regulate the trafficking of ATG9A from the Golgi complex to the peripheral cytoplasm for the formation of autophagosomes by inducing Golgi membrane tubulation and fragmentation (PubMed:21068542) . Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123) . Isoform 2 acts antiapoptotic in neuronal cells; involved in maintenance of mitochondrial morphology and promotes neuronal viability (By similarity) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
SH3GLB1
Host or Source
Rabbit
Protein Name
Endophilin-B1
Gene Name URL
SH3GLB1
Nucleotide Accession Number
NM_001206651

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