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IL1RAP Antibody

CAT: 0247-OACA07147-50ULSize: 50 µLDry Ice: NoHazardous: No
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CAT#:0247-OACA07147-50ULSize:50 µL
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CAS Number
9007-83-4
Gene Name
Interleukin 1 receptor accessory protein
Gene Aliases
C3orf13; IL-1 receptor accessory protein; IL1R3; IL-1RAcP; interleukin-1 receptor 3; interleukin-1 receptor accessory protein; interleukin-1 receptor accessory protein beta.
Gene ID
3556
Accession Number
NP_001161400
Reactivity
Human
Immunogen
Recombinant Human Interleukin-1 receptor accessory protein (21-356AA)
Target
Coreceptor for IL1RL2 in the IL-36 signaling system (By similarity) . Coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Recruits TOLLIP to the signaling complex. Does not bind to interleukin-1 alone; binding of IL1RN to IL1R1, prevents its association with IL1R1 to form a signaling complex. The cellular response is modulated through a non-signaling association with the membrane IL1R2 decoy receptor. Coreceptor for IL1RL1 in the IL-33 signaling system. Can bidirectionally induce pre- and postsynaptic differentiation of neurons by trans-synaptically binding to PTPRD (By similarity) . May play a role in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells (Probable) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
IL1RAP
Host or Source
Rabbit
Protein Name
Interleukin-1 receptor accessory protein
Gene Name URL
IL1RAP
Nucleotide Accession Number
NM_001167928

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