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IL1R2 Antibody

CAT: 0247-OACA07087-50ULSize: 50 µLDry Ice: NoHazardous: No
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CAT#:0247-OACA07087-50ULSize:50 µL
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CAS Number
9007-83-4
Gene Name
Interleukin 1 receptor type 2
Gene Aliases
Antigen CDw121b; CD121 antigen-like family member B; CD121b; CDw121b; IL-1 type II receptor; IL-1R-2; IL1R2c; IL1RB; IL-1R-beta; IL-1RT2; IL-1RT-2; interleukin 1 receptor type II variant 3; interleukin-1 receptor beta; interleukin-1 receptor type 2; interleukin-1 receptor type II; type II interleukin-1 receptor, beta.
Gene ID
7850
Accession Number
NP_001248348
Reactivity
Human|Mouse
Immunogen
Recombinant Human Interleukin-1 receptor type 2 protein (20-320AA)
Target
Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
IL1R2
Host or Source
Rabbit
Protein Name
Interleukin-1 receptor type 2
Gene Name URL
IL1R2
Nucleotide Accession Number
NM_001261419

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