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DHRS2 Antibody

CAT: 0247-OACA06879-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OACA06879-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Dehydrogenase/reductase 2
Gene Aliases
Dehydrogenase/reductase (SDR family) member 2; dehydrogenase/reductase member 2; dehydrogenase/reductase SDR family member 2, mitochondrial; dicarbonyl reductase HEP27; HEP27; protein D; SDR25C1; short chain dehydrogenase/reductase family 25C member 1; short-chain alcohol dehydrogenase family member.
Gene ID
10202
Accession Number
NP_005785
Reactivity
Human
Immunogen
Recombinant Human Dehydrogenase/reductase SDR family member 2, mitochondrial protein (1-300AA)
Target
Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
DHRS2
Host or Source
Rabbit
Protein Name
Dehydrogenase/reductase SDR family member 2, mitochondrial
Gene Name URL
DHRS2
Nucleotide Accession Number
NM_005794

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