ENPP2 Antibody

CAT: 0247-OACA06797-50ULSize: 50 µLDry Ice: NoHazardous: No
CAT#:0247-OACA06797-50ULSize:50 µL
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CAS Number
9007-83-4
Gene Name
Ectonucleotide pyrophosphatase/phosphodiesterase 2
Gene Aliases
ATX; ATX-X; AUTOTAXIN; autotaxin-t; ectonucleotide pyrophosphatase/phosphodiesterase family member 2; E-NPP 2; extracellular lysophospholipase D; LysoPLD; NPP2; PD-IALPHA; PDNP2; phosphodiesterase I/nucleotide pyrophosphatase 2; plasma lysophospholipase D.
Gene ID
5168
Accession Number
NP_001035181
Reactivity
Human
Immunogen
Recombinant Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 protein (564-863AA)
Target
Hydrolyzes lysophospholipids to produce the signaling molecule lysophosphatidic acid (LPA) in extracellular fluids (PubMed:15769751, PubMed:26371182, PubMed:27754931) . Major substrate is lysophosphatidylcholine (PubMed:12176993, PubMed:27754931) . Also can act on sphingosylphosphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP (PubMed:15769751, PubMed:12176993) . Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation (PubMed:11559573) . Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein (PubMed:1733949) . May have a role in induction of parturition (PubMed:12176993) . Possible involvement in cell proliferation and adipose tissue development (Probable) . Tumor cell motility-stimulating factor (PubMed:1733949, PubMed:11559573) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
ENPP2
Host or Source
Rabbit
Protein Name
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
Gene Name URL
ENPP2
Nucleotide Accession Number
NM_001040092

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