Products for Research Use Only
RegisterLogin

RICTOR Antibody

CAT: 0247-OACA06735-100ULSize: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OACA06735-100ULSize:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
RPTOR independent companion of MTOR complex 2
Gene Aliases
AVO3; AVO3 homolog; hAVO3; PIA; pianissimo; rapamycin-insensitive companion of mTOR; TORC2-specific protein AVO3.
Gene ID
253260
Accession Number
NP_001272368
Reactivity
Human
Immunogen
Recombinant Human Rapamycin-insensitive companion of mTOR protein (1-245AA)
Target
Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'. Plays an essential role in embryonic growth and development.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
RICTOR
Host or Source
Rabbit
Protein Name
Rapamycin-insensitive companion of mTOR
Gene Name URL
RICTOR
Nucleotide Accession Number
NM_001285439

Related Products

CatalogName
OACD01074-100ULWAS Antibody
OAMA00822-1MGWAS Antibody
OAMA00821-1MGWAS Antibody
OASG07565-100ULWAS Antibody
OACD00878-100ULAT Antibody
OACD06223-1MLON Antibody
OACD00878-1MLAT Antibody
OAAJ06634-100ULWAS Antibody
OAMA01384-1MGWAS Antibody
OACD01827-1MLAT Antibody

Alternative Products

CatalogName
10R-2232RICTOR antibody

Popular Products