CREB3 Antibody

• Gene Name:

  CAMP responsive element binding protein 3

• Gene Aliases:

  Basic leucine zipper protein; cyclic AMP response element (CRE) -binding protein/activating transcription factor 1; cyclic AMP-responsive element-binding protein 3; leucin zipper proitein; Leucine zipper protein; LUMAN; LZIP; sLZIP; small leucine zipper protein; transcription factor LZIP-alpha.

• Gene ID:

  10488

• Accession Number:

  NP_006359

• Reactivity:

  Human

• Immunogen:

  Recombinant Human Cyclic AMP-responsive element-binding protein 3 protein (1-230AA)

• Target:

  Endoplasmic reticulum (ER) -bound sequence-specific transcription factor that directly binds DNA and activates transcription (PubMed:9271389, PubMed:19779205, PubMed:10984507, PubMed:15845366, PubMed:16940180) . Plays a role in the unfolded protein response (UPR), promoting cell survival versus ER stress-induced apoptotic cell death (PubMed:15845366, PubMed:16940180) . Also involved in cell proliferation, migration and differentiation, tumor suppression and inflammatory gene expression. Acts as a positive regulator of LKN-1/CCL15-induced chemotaxis signaling of leukocyte cell migration (PubMed:19779205, PubMed:15001559, PubMed:17296613) . Associates with chromatin to the HERPUD1 promoter (PubMed:16940180) . Also induces transcriptional activation of chemokine receptors (PubMed:18587271, PubMed:17296613) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format:

  Liquid

• Reconstitution:

  -20°C or -80°C

• Fragment:

  IgG

• NCBI Gene Symbol:

  CREB3

• Host or Source:

  Rabbit

• Protein Name:

  Cyclic AMP-responsive element-binding protein 3

• Gene Name URL:

  CREB3

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_006368