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HIP1 Antibody

CAT: 0247-OACA06585-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OACA06585-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Huntingtin interacting protein 1
Gene Aliases
HIP-I; huntingtin-interacting protein 1; huntingtin-interacting protein I; ILWEQ; SHON; SHONbeta; SHONgamma.
Gene ID
3092
Accession Number
NP_001230127
Reactivity
Human
Immunogen
Recombinant Human Huntingtin-interacting protein 1 protein (410-690AA)
Target
Plays a role in clathrin-mediated endocytosis and trafficking (PubMed:11532990, PubMed:11577110, PubMed:11889126) . Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner (By similarity) . Regulates presynaptic nerve terminal activity (By similarity) . Enhances androgen receptor (AR) -mediated transcription (PubMed:16027218) . May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway (PubMed:11007801) . Binds 3-phosphoinositides (via ENTH domain) (PubMed:14732715) . May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis (PubMed:14732715) . May play a functional role in the cell filament networks (PubMed:18790740) . May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors (PubMed:11007801, PubMed:12163454) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
HIP1
Host or Source
Rabbit
Protein Name
Huntingtin-interacting protein 1
Gene Name URL
HIP1
Nucleotide Accession Number
NM_001243198

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