TRMT112 Antibody

CAT: 0247-OACA06310-50UGSize: 50 µgDry Ice: NoHazardous: No
CAT#:0247-OACA06310-50UGSize:50 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
TRNA methyltransferase activator subunit 11-2
Gene Aliases
HSPC152; HSPC170; hTrm112; multifunctional methyltransferase subunit TRM112-like protein; TRM112; TRM112-like protein; TRMT11-2; tRNA methyltransferase 112 homolog; tRNA methyltransferase 11-2 homolog; tRNA methyltransferase subunit 11-2.
Gene ID
51504
Accession Number
NP_001273011
Reactivity
Human
Immunogen
Recombinant Human tRNA methyltransferase 112 homolog protein (1-125AA)
Target
Acts as an activator of both rRNA/tRNA and protein methyltransferases (PubMed:25851604) . Together with methyltransferase BUD23, methylates the N (7) position of a guanine in 18S rRNA (PubMed:25851604) . The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor (PubMed:18539146) . The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species (PubMed:20308323) . Involved in the pre-rRNA processing steps leading to small-subunit rRNA production (PubMed:25851604) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
TRMT112
Host or Source
Rabbit
Protein Name
Multifunctional methyltransferase subunit TRM112-like protein
Gene Name URL
TRMT112
Nucleotide Accession Number
NM_001286082

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