Products for Research Use Only
RegisterLogin

SPDL1 Antibody

CAT: 0247-OACA05602-100UGSize: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OACA05602-100UGSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
Spindle apparatus coiled-coil protein 1
Gene Aliases
Arsenite-related gene 1 protein; CCDC99; coiled-coil domain-containing protein 99; protein Spindly; rhabdomyosarcoma antigen MU-RMS-40.4A; rrhabdomyosarcoma antigen protein MU-RMS-40.4A; Spindle apparatus coiled-coil domain-containing protein 1.
Gene ID
54908
Accession Number
NP_001316570
Reactivity
Human
Immunogen
Recombinant Human Protein Spindly protein (1-300AA)
Target
Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment (PubMed:17576797, PubMed:19468067) . Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (PubMed:25035494) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
SPDL1
Host or Source
Rabbit
Protein Name
Protein Spindly
Gene Name URL
SPDL1
Nucleotide Accession Number
NM_001329641

Related Products

CatalogName
OCOA09923-20UGSPDL1 Protein Lysate
OKEH08283-96WSPDL1 ELISA Kit (Human)
AAP83651-100UGSPDL1 Peptide - middle region (AAP83651)
OKEH08283SPDL1 ELISA Kit (Human) (OKEH08283)
OACD01074-100ULWAS Antibody
OAMA00822-1MGWAS Antibody
OAMA00821-1MGWAS Antibody
OASG07565-100ULWAS Antibody
OACD00878-100ULAT Antibody
OACD06223-1MLON Antibody

Alternative Products

CatalogName
MBS7124311-01SPDL1 Antibody

Popular Products