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MRGPRX2 Antibody

CAT: 0247-OACA05547-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OACA05547-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
MAS related GPR family member X2
Gene Aliases
G protein-coupled receptor MRGX2; Mas-related G protein-coupled receptor G3; MAS-related GPR, member X2; mas-related G-protein coupled receptor member X2; MGRG3; MRGX2.
Gene ID
117194
Accession Number
NP_001290544
Reactivity
Human, Mouse
Immunogen
Recombinant Human Mas-related G-protein coupled receptor member X2 protein (286-330AA)
Target
Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core (PubMed:25517090) . Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction (By similarity) . Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Western blot
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
Varies by lot. See vial for concentration.
Format
Liquid// 0.01M PBS (pH 7.4) with 0.03% Proclin300 and 50% glycerol
Reconstitution
Upon receipt, store at -20° C or -80° C. Avoid repeated freeze/thaw cycles.
Fragment
IgG
NCBI Gene Symbol
MRGPRX2
Host or Source
Rabbit
Protein Name
Mas-related G-protein coupled receptor member X2
Gene Name URL
MRGPRX2
Nucleotide Accession Number
NM_001303615

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