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RPUSD4 Antibody

CAT: 0247-OACA05468-50UGSize: 50 µgDry Ice: NoHazardous: No
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CAT#:0247-OACA05468-50UGSize:50 µg
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CAS Number
9007-83-4
Gene Name
RNA pseudouridine synthase D4
Gene Aliases
Mitochondrial RNA pseudouridine synthase RPUSD4; RNA pseudouridylate synthase domain containing 4; RNA pseudouridylate synthase domain-containing protein 4.
Gene ID
84881
Accession Number
NP_001138299
Reactivity
Human
Immunogen
Recombinant Human Mitochondrial RNA pseudouridine synthase RPUSD4 protein (41-240AA)
Target
Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of different mitochondrial RNA substrates. Acts on position 1397 in 16S mitochondrial ribosomal RNA (16S mt-rRNA) . This modification is required for the assembly of 16S mt-rRNA into a functional mitochondrial ribosome (PubMed:27974379) . Acts on position 39 in mitochondrial tRNA (Phe) (PubMed:28082677) . As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA, controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation (PubMed:27667664) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
RPUSD4
Host or Source
Rabbit
Protein Name
Mitochondrial RNA pseudouridine synthase RPUSD4
Gene Name URL
RPUSD4
Nucleotide Accession Number
NM_001144827

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