CBX2 Antibody

• Gene Name:

  Chromobox 2

• Gene Aliases:

  CDCA6; cell division cycle associated 6; chromobox homolog 2 (Pc class homolog, Drosophila) ; chromobox protein homolog 2; M33; modifier 3; Pc class homolog; SRXY5.

• Gene ID:

  84733

• Accession Number:

  NP_005180

• Reactivity:

  Human|Mouse

• Immunogen:

  Recombinant Human Chromobox protein homolog 2 protein (1-211AA)

• Target:

  Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development (PubMed:21282530) . PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (PubMed:21282530) . Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3) (By similarity) . Plays a role in the lineage differentiation of the germ layers in embryonic development (By similarity) . Involved in sexual development, acting as activator of NR5A1 expression (PubMed:19361780) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot

• Purification:

  Protein G Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format:

  Liquid

• Reconstitution:

  -20°C or -80°C

• Fragment:

  IgG

• NCBI Gene Symbol:

  CBX2

• Host or Source:

  Rabbit

• Protein Name:

  Chromobox protein homolog 2

• Gene Name URL:

  CBX2

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_005189