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STT3A Antibody

CAT: 0247-OACA03739-50UGSize: 50 µgDry Ice: NoHazardous: No
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CAT#:0247-OACA03739-50UGSize:50 µg
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CAS Number
9007-83-4
Gene Name
STT3 oligosaccharyltransferase complex catalytic subunit A
Gene Aliases
B5; dolichyl-diphosphooligosaccharide protein glycotransferase; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A; integral membrane protein 1; integral transmembrane protein 1; ITM1; oligosaccharyl transferase subunit STT3A; STT3, subunit of the oligosaccharyltransferase complex, homolog A; STT3-A; STT3A, catalytic subunit of the oligosaccharyltransferase complex; STT3A, subunit of the oligosaccharyltransferase complex (catalytic) ; TMC; transmembrane conserved; transmembrane protein TMC.
Gene ID
3703
Accession Number
NP_001265432
Reactivity
Human
Immunogen
Recombinant Human Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A protein (39-114AA)
Target
Catalytic subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER) . SST3A seems to be involved in complex substrate specificity. STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient post-translational glycosylation and mediate glycosylation of sites that have been skipped by STT3A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
STT3A
Host or Source
Rabbit
Protein Name
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A
Gene Name URL
STT3A
Nucleotide Accession Number
NM_001278503

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