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PLA2G16 Antibody

CAT: 0247-OACA03451-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OACA03451-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Phospholipase A and acyltransferase 3
Gene Aliases
Adipose-specific phospholipase A2; adipose-specific PLA2; AdPLA; Ca-independent phospholipase A1/2; group XVI phospholipase A1/A2; group XVI phospholipase A2; HRAS-like suppressor 1; HRAS-like suppressor 3; HRASLS3; H-rev 107 protein homolog; HREV107; H-REV107; HREV107-1; H-REV107-1; HREV107-3; HRSL3; phospholipase A and acyltransferase 3; phospholipase A/acyltransferase-3; phospholipase A2 group XVI; PLA2G16; PLAAT-3; renal carcinoma antigen NY-REN-65.
Gene ID
11145
Accession Number
NP_001121675
Reactivity
Human
Immunogen
Recombinant Human HRAS-like suppressor 3 protein (1-132AA)
Target
Lipid-modifying enzyme that acts as major regulator of adipocyte lipolysis by catalyzing the release of fatty acids from phospholipids in adipose tissue (PubMed:19615464, PubMed:19047760, PubMed:20837014, PubMed:22605381, PubMed:22923616) . Shows phospholipase A1 and A2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE) (PubMed:19615464, PubMed:19047760, PubMed:20837014, PubMed:22605381, PubMed:22923616) . For most substrates, phospholipase A1 activity is much higher than phospholipase A2 activity (PubMed:19047760) . Phospholipase activity causes decreased intracellular levels of ether-type lipids, affecting peroxisome metabolism (By similarity) . May also have acyltransferase activity: catalyzes both N-acylation of phosphatidylethanolamine to form N-acyl-phosphatidylethanolamine and O-acylation of lyso-phosphatidylcholines to form phosphatidylcholines (PubMed:22605381, PubMed:25383759) . The relevance of acyltransferase activity in vivo is however unclear and would require additional evidences (PubMed:22605381, PubMed:25383759) . Also has weak lysophospholipase activity (By similarity) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
Varies by lot. See vial for exact concentration.
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
PLAAT3
Host or Source
Rabbit
Protein Name
HRAS-like suppressor 3
Gene Name URL
PLAAT3
Nucleotide Accession Number
NM_001128203

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