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KCNA6 Antibody

CAT: 0247-OACA03181-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OACA03181-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Potassium voltage-gated channel subfamily A member 6
Gene Aliases
HBK2; human brain potassium channel-2; KV1.6; potassium channel, voltage gated shaker related subfamily A, member 6; potassium voltage-gated channel subfamily A member 6; potassium voltage-gated channel, shaker-related subfamily, member 6; PPP1R96; protein phosphatase 1, regulatory subunit 96; voltage-gated potassium channel HBK2; voltage-gated potassium channel protein Kv1.6; voltage-gated potassium channel subunit Kv1.6.
Gene ID
3742
Accession Number
NP_002226
Reactivity
Human
Immunogen
Recombinant Human Potassium voltage-gated channel subfamily A member 6 protein (1-171AA)
Target
Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient (PubMed:2347305, PubMed:14575698) . The channel alternates between opened and closed conformations in response to the voltage difference across the membrane (PubMed:2347305, PubMed:14575698) . Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA6, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel (By similarity) . Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation (By similarity) . Homotetrameric channels display rapid activation and slow inactivation (PubMed:2347305) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
KCNA6
Host or Source
Rabbit
Protein Name
Potassium voltage-gated channel subfamily A member 6
Gene Name URL
KCNA6
Nucleotide Accession Number
NM_002235

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