CHM Antibody

CAT: 0247-OACA02745-100UGSize: 100 µgDry Ice: NoHazardous: No
CAT#:0247-OACA02745-100UGSize:100 µg
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CAS Number
9007-83-4
Gene Name
CHM Rab escort protein
Gene Aliases
CHM, Rab escort protein 1; choroideremia (Rab escort protein 1) ; Choroideremia protein; DXS540; GGTA; HSD-32; Rab escort protein 1; rab proteins geranylgeranyltransferase component A 1; REP-1; TCD; TCD protein.
Gene ID
1121
Accession Number
NP_000381
Reactivity
Human
Immunogen
Recombinant Human Rab proteins geranylgeranyltransferase component A 1 protein (1-653AA)
Target
Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
CHM
Host or Source
Rabbit
Protein Name
Rab proteins geranylgeranyltransferase component A 1
Gene Name URL
CHM
Nucleotide Accession Number
NM_000390

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