BLOC1S1 Antibody

• Gene Name:

  Biogenesis of lysosomal organelles complex 1 subunit 1

• Gene Aliases:

  Biogenesis of lysosome-related organelles complex 1 subunit 1; BLOC-1 subunit 1; BLOS1; BORCS1; GCN5 (general control of amino-acid synthesis, yeast, homolog) -like 1; GCN5 general control of amino-acid synthesis 5-like 1; GCN5L1; GCN5-like protein 1; MICoA; MTA1-interacting coactivator; Protein RT14; RT14.

• Gene ID:

  2647

• Accession Number:

  NP_001478

• Reactivity:

  Human

• Immunogen:

  Recombinant Human Biogenesis of lysosome-related organelles complex 1 subunit 1 protein (1-153AA)

• Target:

  Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension (PubMed:17182842) . As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed:25898167) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Western blot

• Purification:

  Protein G Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format:

  Liquid

• Reconstitution:

  -20°C or -80°C

• Fragment:

  IgG

• NCBI Gene Symbol:

  BLOC1S1

• Host or Source:

  Rabbit

• Protein Name:

  Biogenesis of lysosome-related organelles complex 1 subunit 1

• Gene Name URL:

  BLOC1S1

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001487