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CASQ1 Antibody

CAT: 0247-OACA02702-50UGSize: 50 µgDry Ice: NoHazardous: No
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CAT#:0247-OACA02702-50UGSize:50 µg
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CAS Number
9007-83-4
Gene Name
Calsequestrin 1
Gene Aliases
Calmitin; calmitine; calsequestrin 1 (fast-twitch, skeletal muscle) ; Calsequestrin, skeletal muscle isoform; calsequestrin-1; CASQ; PDIB1; VMCQA.
Gene ID
844
Accession Number
NP_001222
Reactivity
Human|Mouse
Immunogen
Recombinant Human Calsequestrin-1 protein (127-396AA)
Target
Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle (PubMed:28895244) . Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca (2+) ions (PubMed:28895244) . Regulates the release of lumenal Ca (2+) via the calcium release channel RYR1; this plays an important role in triggering muscle contraction. Negatively regulates store-operated Ca (2+) entry (SOCE) activity (PubMed:27185316) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
CASQ1
Host or Source
Rabbit
Protein Name
Calsequestrin-1
Gene Name URL
CASQ1
Nucleotide Accession Number
NM_001231

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