Products for Research Use Only
RegisterLogin

TCPTP Antibody

CAT: 0247-OABB01984-100UGSize: 100 µg/VialDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OABB01984-100UGSize:100 µg/Vial
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
Mitofusin 2
Gene Aliases
CMT2A; CMT2A2; CMT2A2A; CMT2A2B; CPRP1; HMSN6A; HSG; hyperplasia suppressor; MARF; mitochondrial assembly regulatory factor; mitofusin-2; transmembrane GTPase MFN2.
Gene ID
9927
Swiss Prot
P09467
Reactivity
Human
Immunogen
A synthesized peptide derived from human Mitofusin 2
Clonality
Recombinant Monoclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed:11181170, PubMed:11950885, PubMed:28114303) . Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events (PubMed:28114303) . Overexpression induces the formation of mitochondrial networks (PubMed:28114303) . Membrane clustering requires GTPase activity and may involve a major rearrangement of the coiled coil domains (Probable) . Plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes (By similarity) . Plays an important role in the regulation of vascular smooth muscle cell proliferation (By similarity) . Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) (PubMed:23620051) . Is required for PRKN recruitment to dysfunctional mitochondria (PubMed:23620051) . Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress (By similarity) . Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions (By similarity) .
Format
Liquid
Reconstitution
-20°C or -80°C
NCBI Gene Symbol
MFN2
Protein Name
Mitofusin-2
Gene Name URL
MFN2

Related Products

CatalogName
OACD01074-100ULWAS Antibody
OAMA00822-1MGWAS Antibody
OAMA00821-1MGWAS Antibody
OASG07565-100ULWAS Antibody
OACD00878-100ULAT Antibody
OACD06223-1MLON Antibody
OACD00878-1MLAT Antibody
OACD06223-100ULON Antibody
OAMA00772-1MGWAS Antibody
OACD01074-1MLWAS Antibody

Alternative Products

CatalogName
MBS833344TCPTP antibody
C19538-50uLTCPTP Antibody [K1C16]
RQ6673TCPTP Antibody / PTPN2
MBS177778-01Anti-TCPTP Antibody
HY-P87102-01TCPTP Antibody (YA6795, Rabbit)
TMAY-03465Anti-TCPTP Antibody (6E858)
GTR18215920-01Rabbit PTPN2/TCPTP Antibody
GTR18962993TCPTP Antibody Blocking peptide
TA356510TCPTP (PTPN2) Rabbit Polyclonal Antibody
PB9501Anti-TCPTP/PTPN2 Antibody Picoband®

Popular Products