Products for Research Use Only
RegisterLogin

PTPN11 Polyclonal Antibody

CAT: 0247-OABB00811-100UGSize: 100 µg/VialDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OABB00811-100UGSize:100 µg/Vial
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
Gene Aliases
ATP2B; ATPase Ca++ transporting cardiac muscle slow twitch 2; ATPase, Ca++ dependent, slow-twitch, cardiac muscle-2; calcium pump 2; Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform; cardiac Ca2+ ATPase; DAR; DD; endoplasmic reticulum class 1/2 Ca (2+) ATPase; sarcoplasmic/endoplasmic reticulum calcium ATPase 2; SERCA2; SR Ca (2+) -ATPase 2.
Gene ID
488
Swiss Prot
P14324
Reactivity
Human
Immunogen
A synthesized peptide derived from Human ATP2A2
Clonality
Recombinant Monoclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Isoform 2 is involved in the regulation of the contraction/relaxation cycle (PubMed:16402920) . Acts as a regulator of TNFSF11-mediated Ca (2+) signaling pathways via its interaction with TMEM64 which is critical for the TNFSF11-induced CREB1 activation and mitochondrial ROS generation necessary for proper osteoclast generation. Association between TMEM64 and SERCA2 in the ER leads to cytosolic Ca (2+) spiking for activation of NFATC1 and production of mitochondrial ROS, thereby triggering Ca (2+) signaling cascades that promote osteoclast differentiation and activation (By similarity) .
Format
Liquid
Reconstitution
-20°C or -80°C
NCBI Gene Symbol
ATP2A2
Protein Name
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
Gene Name URL
ATP2A2

Related Products

CatalogName
OASG06641-100ULPTPN11 Antibody
OAAJ07558-100ULPTPN11 Antibody
OAAB18283-100ULPTPN11 Antibody
OAAN03072-200ULPTPN11 Antibody (Phospho-Tyr580)
OAAJ02699-100ULPTPN11 Antibody (Phospho-Tyr542)
OAAN03072-50ULPTPN11 Antibody (Phospho-Tyr580)
OAAJ02700-100ULPTPN11 Antibody (Phospho-Tyr580)
OASG06643-100ULPTPN11 Antibody - middle region
OASG06639-100ULPTPN11 Antibody (Phospho-Tyr580)
OACA12675-100ULPTPN11 Recombinant Antibody [7A1] (OACA12675)

Alternative Products

CatalogName
MBS2525811-01PTPN11 Polyclonal Antibody
MBS8508807-01PTPN11 Antibody (Rabbit Polyclonal)
C27703PTPN11 Polyclonal Conjugated Antibody
GTR18038024-01PTPN11 Rabbit Polyclonal Antibody
GWB-BBP115Polyclonal Anti-(PTPN11) Antibody
HC400014-01Anti-PTPN11 Polyclonal Antibody

Popular Products