COL4A2 Antibody

• Gene Name:

  Interleukin 1 receptor type 1

• Gene Aliases:

  CD121 antigen-like family member A; CD121A; D2S1473; IL1R; IL-1R-1; IL1RA; IL-1R-alpha; IL-1RT1; IL-1RT-1; interleukin 1 receptor alpha, type I; interleukin-1 receptor alpha; interleukin-1 receptor type 1; interleukin-1 receptor type I; P80.

• Gene ID:

  3554

• Swiss Prot:

  P09429

• Reactivity:

  Human

• Immunogen:

  A synthesized peptide derived from Human IL1R1

• Clonality:

  Recombinant Monoclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Dilution:

  Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells (PubMed:10653850) .

• Format:

  Liquid

• Reconstitution:

  -20°C or -80°C

• NCBI Gene Symbol:

  IL1R1

• Protein Name:

  Interleukin-1 receptor type 1

• Gene Name URL:

  IL1R1

• CAS Number:

  9007-83-4