MTA1 Polyclonal Antibody

CAT: 0247-OABB00437-100UGSize: 100 µg/VialDry Ice: NoHazardous: No
CAT#:0247-OABB00437-100UGSize:100 µg/Vial
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Heterogeneous nuclear ribonucleoprotein K
Gene Aliases
AUKS; CSBP; dC-stretch binding protein; heterogeneous nuclear ribonucleoprotein K; HNRPK; transformation upregulated nuclear protein; Transformation up-regulated nuclear protein; TUNP.
Gene ID
3190
Swiss Prot
P68431
Reactivity
Human
Immunogen
A synthesized peptide derived from human HNRNPK
Clonality
Recombinant Monoclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
One of the major pre-mRNA-binding proteins. Binds tenaciously to poly (C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly (C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity) . As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.
Format
Liquid
Reconstitution
-20°C or -80°C
NCBI Gene Symbol
HNRNPK
Protein Name
Heterogeneous nuclear ribonucleoprotein K
Gene Name URL
HNRNPK

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