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LDLRAP1 Antibody

CAT: 0247-OAAN03635-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OAAN03635-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Low density lipoprotein receptor adaptor protein 1
Gene Aliases
ARH, ARH1, ARH2, FHCB1, FHCB2, FHCL4
Gene ID
26119
Swiss Prot
Q5SW96
Accession Number
NP_056442.2
Reactivity
Human, Mouse
Immunogen
Recombinant Protein
Target
Adapter protein (clathrin-associated sorting protein (CLASP) ) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts) . May be required for LDL binding and internalization but not for receptor clustering in coated pits. May facilitate the endocytocis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits. May also be involved in the internalization of other LDLR family members. Binds to phosphoinositides, which regulate clathrin bud assembly at the cell surface.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification
Affinity purification
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
Store at +4C. For long term storage, aliquote and store at -20C. Avoid freeze/thaw cycles.
Molecular Weight
34 kDa
Fragment
IgG
NCBI Gene Symbol
LDLRAP1
Host or Source
Rabbit
Protein Name
Iron-sulfur cluster assembly enzyme ISCU, mitochondrial
Gene Name URL
LDLRAP1
Nucleotide Accession Number
NM_015627.2

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