USP5 Antibody

• Gene Name :

  Ubiquitin specific peptidase 5

• Gene Aliases :

  ISOT

• Gene ID :

  8078

• Swiss Prot :

  P45974

• Accession Number :

  NP_001092006.1

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant Protein

• Target :

  Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.

• Clonality :

  Polyclonal

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification :

  Affinity purification

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format :

  Liquid

• Reconstitution :

  Store at +4C. For long term storage, aliquote and store at -20C. Avoid freeze/thaw cycles.

• Molecular Weight :

  96 kDa

• Fragment :

  IgG

• NCBI Gene Symbol :

  USP5

• Host or Source :

  Rabbit

• Protein Name :

  Signal transducing adapter molecule 1

• Gene Name URL :

  USP5

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_001098536.1