SPDYA Antibody

• Gene Name:

  Speedy/RINGO cell cycle regulator family member A

• Gene Aliases:

  Epididymis secretory sperm binding protein; hSpy/Ringo A; rapid inducer of G2/M progression in oocytes A; RINGO A; RINGO3; RINGOA; SPDY1; speedy homolog A; speedy protein A; speedy-1; SPY1.

• Gene ID:

  245711

• Swiss Prot:

  Q5MJ70

• Accession Number:

  NP_001008779.1

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  SPDYA

• Target:

  Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1 and CDK2 (PubMed:12972555) . Contributes to CDK2 activation without promoting CDK2 phosphorylation, by inducing a conformation change of the CDK2 T-loop that obstructs the substrate-binding cleft prior to kinase activation (PubMed:28666995) . Mediates cell survival during the DNA damage process through activation of CDK2 (PubMed:12839962) .

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  Western blot

• Purification:

  Affinity purification

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format:

  Liquid

• Reconstitution:

  Store at +4C. For long term storage, aliquote and store at -20C. Avoid freeze/thaw cycles.

• Molecular Weight:

  36kDa

• Fragment:

  IgG

• NCBI Gene Symbol:

  SPDYA

• Host or Source:

  Rabbit

• Protein Name:

  Speedy protein A

• Gene Name URL:

  SPDYA

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001008779.1