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NUDT15 Antibody

CAT: 0247-OAAN02710-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OAAN02710-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Nudix hydrolase 15
Gene Aliases
MTH2, NUDT15D
Gene ID
55270
Swiss Prot
Q9NV35
Accession Number
NP_001291674.1
Reactivity
Human, Rat
Immunogen
Recombinant protein of human NUDT15
Target
This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity purified against immunogen
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Reconstitution
Store at -20C. Avoid repeated freeze/thaw cycles.
Molecular Weight
19 kDa
Fragment
IgG
NCBI Gene Symbol
NUDT15
Host or Source
Rabbit
Protein Name
Probable 8-oxo-dGTP diphosphatase NUDT15
Gene Name URL
NUDT15
Nucleotide Accession Number
NM_001304745.1

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