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MBNL1 Antibody

CAT: 0247-OAAN02582-200ULSize: 200 µLDry Ice: NoHazardous: No
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CAT#:0247-OAAN02582-200ULSize:200 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Muscleblind like splicing regulator 1
Gene Aliases
EXP, MBNL
Gene ID
4154
Swiss Prot
Q9NR56
Accession Number
NP_001300986.1
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human MBNL1
Target
This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification
Affinity purified against immunogen
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Reconstitution
Store at -20C. Avoid repeated freeze/thaw cycles.
Molecular Weight
42 kDa
Fragment
IgG
NCBI Gene Symbol
MBNL1
Host or Source
Rabbit
Protein Name
Muscleblind-like protein 1
Gene Name URL
MBNL1
Nucleotide Accession Number
NM_001314057.1

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