ACTL6A Antibody

CAT: 0247-OAAN01251-100ULSize: 100 µLDry Ice: NoHazardous: No
CAT#:0247-OAAN01251-100ULSize:100 µL
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CAS Number
9007-83-4
Gene Name
Actin like 6A
Gene Aliases
Arp4, ACTL6, BAF53A, INO80K, ARPN-BETA
Gene ID
86
Swiss Prot
O96019
Accession Number
NP_004292.1
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human ACTL6A
Target
This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF, IP, CHIP
Purification
Affinity purified against immunogen
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Reconstitution
Store at -20C. Avoid repeated freeze/thaw cycles.
Molecular Weight
47 kDa
Fragment
IgG
NCBI Gene Symbol
ACTL6A
Host or Source
Rabbit
Protein Name
Actin-like protein 6A
Gene Name URL
ACTL6A
Nucleotide Accession Number
NM_004301.4

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