CBR4 Antibody

• Gene Name:

  Carbonyl reductase 4

• Gene Aliases:

  3-ketoacyl-[acyl-carrier-protein] reductase beta subunit;3-oxoacyl-[acyl-carrier-protein] reductase; carbonic reductase 4; carbonyl reductase family member 4; KAR beta subunit; quinone reductase CBR4; SDR45C1; short chain dehydrogenase/reductase family 45C member 1.

• Gene ID:

  84869

• Swiss Prot:

  Q8N4T8

• Accession Number:

  NP_116172.2

• Reactivity:

  Human, Rat

• Immunogen:

  CBR4

• Target:

  The heterotetramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis (PubMed:19571038, PubMed:25203508) . Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD (PubMed:25203508) . The homotetramer has NADPH-dependent quinone reductase activity (PubMed:19000905) . Both homotetramer and the heterotetramer have broad substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro) (PubMed:19000905, PubMed:19571038, PubMed:25203508) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  Western blot

• Purification:

  Affinity purified against immunogen

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format:

  Liquid

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Reconstitution:

  Store at -20C. Avoid repeated freeze/thaw cycles.

• Molecular Weight:

  25kDa

• Fragment:

  IgG

• NCBI Gene Symbol:

  CBR4

• Host or Source:

  Rabbit

• Protein Name:

  Carbonyl reductase family member 4

• Gene Name URL:

  CBR4

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_032783.4